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IMMUNOLOGY2024™

May 3–7, 2024 | Chicago, Illinois

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 Monday, May 6, 2024     11:30 AM – 12:45 PM ET     Exhibit Hall F1

Heterogeneity and Dynamics of Autoreactive B Cells

Innate receptors CD21 and TLR7 attune tissue dynamics and drive extrafollicular evolution of autoreactive B cells

Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 595
Abstract ID: 4607

Presenting Author:
Danni Y Zhu, Harvard Med. Sch., Boston Children's Hosp., Harvard Med. Sch.

Co-Authors:
Daniel P Maurer, Ragon Inst. of MGH, MIT, and Harvard; Carlos Castrillon, Emory Univ. Sch. of Med.; Yixiang Deng, Ragon Inst. of MGH, MIT, and Harvard; Faez AN Mohamed, Ragon Inst. of MGH, MIT, and Harvard; Minghe Ma, Boston Children’s Hosp., Harvard Med. Sch.; Aaron G Schmidt, Ragon Inst. of MGH, MIT, and Harvard; Daniel Lingwood, Ragon Inst. of MGH, MIT, and Harvard; Michael Carroll, Boston Children’s Hosp., Harvard Med. Sch.


IDO2 drives autoantibody production and joint inflammation by repressing Runx1 function in B cells

Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 597
Abstract ID: 4339

Presenting Author:
Laura Mandik-Nayak, Lankenau Inst. for Med. Res., Maine Line Hlth.

Co-Authors:
Lauren M.F. Merlo, Lankenau Inst. for Med. Res., Maine Line Hlth.; Weidan Peng, Lankenau Inst. for Med. Res., Maine Line Hlth.; James D Montgomery, Lankenau Inst. for Med. Res., Maine Line Hlth.


TLR9 regulates tolerance of developing and mature anti-DNA B cells

Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 601
Abstract ID: 5184

Presenting Author:
Kevin M Nickerson, Univ. of Pittsburgh Sch. of Med.

Co-Authors:
Anthony D Marinov, Univ. of Pittsburgh Sch. of Med.; Yujuan Wang, Univ. of Pittsburgh Sch. of Med.; Jaime L Cullen, Yale Sch. of Med.; Aiden Brown, Univ. of Pittsburgh Sch. of Med.; Brady Marburger, Univ. of Pittsburgh Sch. of Med.; Kayla B Thomas, Univ. of Pittsburgh Sch. of Med.; Kassandra J Baron, Univ. of Pittsburgh Sch. of Med.; Mark J Shlomchik, Univ. of Pittsburgh Sch. of Med.


Heterogeneity of B cells in the immunoregulatory niche at the cribriform plate during EAE

Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 603
Abstract ID: 5598

Presenting Author:
Kristof G Kovacs, Univ. of Wisconsin, Madison

Co-Authors:
Collin Laaker, Univ. of Wisconsin, Madison; Zsuzsanna Fabry, Univ. of Wisconsin, Madison


Defining Immunogenomic Signatures in B Cell-Mediated Autoimmunities

Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 605
Abstract ID: 5570

Presenting Author:
Easton E Ford, Univ. of Louisville Sch. of Med.

Co-Authors:
Veenasravani Pendyala, Univ. of Louisville; Minh C Pham, Yale Sch. of Med.; Soumya S Yandamuri, Yale Sch. of Med.; Oscar L Rodriguez, Univ. of Louisville Sch. of Med.; Uddalok Jana, Univ. of Louisville Sch. of Med.; Elizabeth A Hudson, Univ. of Louisville Sch. of Med.; Lindsay Young, Yale Sch. of Med.; Kevin C O’Connor, Yale Sch. of Med.; Corey T Watson, Univ. of Louisville Sch. of Med.; Melissa L Smith, Univ. of Louisville Sch. of Med.


The complex role of somatic hypermutation in supporting insulin recognition by B lymphocytes in at-risk type 1 diabetes participants

Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 609
Abstract ID: 4626

Presenting Author:
Lindsay Bass, Vanderbilt Univ.

Co-Authors:
Tommi Taylor, Vanderbilt Univ. Med. Ctr.; Mason Forchetti, Vanderbilt Univ. Med. Ctr.; Steven Scaglione, Vanderbilt Univ. Med. Ctr.; Alaina Skellett, Vanderbilt Univ. Med. Ctr.; Anika Mahajan, Vanderbilt Univ. Med. Ctr.; Daniel Moore, Vanderbilt Univ. Med. Ctr.; Scott Smith, Vanderbilt Univ. Med. Ctr.; Rachel Bonami, Vanderbilt Univ. Med. Ctr.


The emerging role of Aiolos in regulating B and T cell tolerance

Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 613
Abstract ID: 5723

Presenting Author:
Mariam A Salem, Ohio State Univ. Col. of Med.

Co-Authors:
Kruthika Sharma, Ohio State Univ.; Melissa R Leonard, Ohio State Univ.; Srijana Pokhrel, Ohio State Univ.; Eugene M Oltz, Ohio State Univ. Col. of Med.; Kenneth J Oestreich, Ohio State Univ. Col. of Med.; Patrick L Collins, Ohio State Univ. Col. of Med.


Autoreactive IgA antibodies are high prevalent and associated with clinical manifestations in systemic lupus erythematosus, systemic scleroderma and idiopathic inflammatory myositis

Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 617
Abstract ID: 4970

Presenting Author:
Quanzhen Li, GeneCopoeia, Univ. of Texas Southwestern Med. Ctr.

Co-Authors:
Junxia Wei, GeneCopoeia; Hui Luo, Xiangya Hosp.; Honglin Zhu, Xiangya Hosp.; Chengsong Zhu, Univ. of Texas Southwestern Med. Ctr.

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IMMUNOLOGY2024™

May 3–7, 2024
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