Monday, May 6, 2024     8:00 AM – 11:30 AM ET     Skyline Ballroom W375C

Major Symposium E

New Insights into Thymic Selection, Tolerance, and Regeneration

Chairs
Kristin A. Hogquist, Univ. of Minnesota Med. Sch., USA
Adrian C. Hayday, King’s Col. London, GBR

Speakers
Kristin , A. Hogquist, Univ. of Minnesota Med. Sch., USA, Sterile interferons activate thymic APC to promote both diversity and tolerance
Lauren I. R. Ehrlich, Univ. of Texas, Austin, USA, Homeostasis and activation of heterogeneous thymic dendritic cells are differentially regulated by distinct thymocyte subsets
Alexandra M. Hoyt-Miggelbrink, Duke Univ., USA, Developing thymocytes cue in unique subsets of neurons to support optimal thymic architecture
Jakub Abramson, Weizmann Inst. of Sci., ISR, HECking the sexual dimorphism of the immune response
Sarah A. Wedemeyer, UT Hlth. San Antonio Long Sch. of Med., USA, A dynamic paracrine FGF21-mTORC1/mTORC2 signaling axis regulates thymus function across the lifespan
James M. Gardner, UCSF, USA, Extrathymic Aire-expressing cells in immune homeostasis
Adrian C. Hayday, King’s Col. London, GBR, BTNL-dependent γδ T cell selection: from murine fetal thymus to human genetic